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National Association For Continuing Education

Course Directors
Gregg Sherman, MD
Chief Medical Officer, NACE
Plantation, FL

Deborah Paschal, CRNP
Clinical Nurse Practitioner
Cardiothoracic Surgery Division
Penn-Presbyterian Medical Center
Philadelphia, PA

Medical Writer
Josh Kilbridge
Kilbride Associates Healthcare Communications
San Francisco, CA

Susan Collazo, RN, MSN, ARNP-BC
Thoracic Surgery Nurse Practitioner
Northwestern Memorial Hospital
Chicago, IL

Frank Rahaghi, MD, MHS, FCCP
Chairman, Department of Pulmonary Medicine
Head, Pulmonary Education and Rehabilitation
Cleveland Clinic Florida
Weston, FL

: Chronic Obstructive Pulmonary Disease and Alpha-1 Antitrypsin Deficiency: Closing the Gaps in Care
Activity/Course #:
: NCME329
: Free
Release/Start Date:
: Mar 14 2017
Expiration Date:
: Mar 13 2018
: Alpha-1
Target Audience:
: Primary Care Providers
: Monograph
Estimated Time To Complete CME Activity:
: 1.0 Hour
: 1.0 AMA PRA Category I Credit(s)
1.0 AANP Contact hour(s) which includes 0.25 pharmacology hour(s)
Hardware/Software Requirements:
Chronic obstructive pulmonary disease (COPD) is a common and complex condition that affects millions of Americans. Primary care clinicians see these patients routinely and are familiar with the challenges of diagnosis, assessment, and effective management. Unfortunately, many patients with COPD remain undiagnosed and untreated and continue to suffer functional limitations and reduced quality of life. The disease is also heterogeneous, with multiple pathophysiologic mechanisms, risk factors, and clinical presentations. One contributor to COPD that is widely underrecognized is alpha-1 antitrypsin deficiency (AATD). This enzyme deficiency is a genetic condition that increases risk for emphysema and other conditions, leading to accelerated decline in lung function and increased mortality. Specific tests and effective therapies for AATD are available and can slow the progression of emphysema in affected patients – but these tests and treatments are often ignored.

This monograph reviews the diagnosis and impact of COPD, the role of AATD, and approaches to the treatment of COPD and AATD in primary care settings.

Learning Objective(s):

After completing this program participants should be able to:

  1. Discuss the pathophysiology of alpha-1 antitrypsin deficiency (AATD)
  2. Demonstrate how to diagnose AATD patients
  3. Incorporate AATD testing into chronic obstructive pulmonary disease (COPD) management algorithms
  4. Evaluate treatment options for patients with AATD

How To Obtain Your CME Certificate

         1. Register for the course at
         2. View the content.
         3. Complete and submit the post-test and evaluation.
         4. A minimum passing score of 80% must be earned on the post-test in order to complete the CME
         5. Print your CME certificate.
Sponsored and Certified By
National Association for Continuing Education
Accreditation Designation Statement
The National Association for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The National Association for Continuing Education designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should only claim the credit commensurate with the extent of their participation in the activity.

National Association for Continuing Education is approved as a provider of nurse practitioner continuing education by the American Association of Nurse Practitioners. AANP Provider Number 121222. This program has been approved for 1.0 contact hour of continuing education(which includes 0.25 pharmacology hours).
Faculty Disclosure Policy
Policy on Faculty and Provider Disclosure: It is the policy of the National Association for Continuing Education to ensure fair balance, independence, objectivity and scientific rigor in all activities. All faculty participating in CME activities sponsored by the National Association for Continuing Education are required to present evidence-based data, identify and reference off-label product use and disclose all relevant financial relationships with those supporting the activity or others whose products or services are discussed. Faculty disclosures are provided below.

Franck Rahaghi, MD, MHS, FCCP, Faculty, serves as a speaker, consultant and researcher for Baxter/Shire, CSL Behring, and Grifols.

Susan Collazo, CRNP, Faculty, serves has no financial relationships with commercial interests to disclose.

Gregg Sherman, MD, Co-Course Director, has no relationships to disclose.

Deborah Paschal, CRNP, Co-Course Director, has no relationships to disclose.

Josh Kilbridge, Medical Writer, has no relationships to disclose.

Harvey C. Parker, Ph.D., Activity Planning Committee, has no relationships to disclose.

Michelle Frisch, MPH, Activity Planning Committee, has no relationships to disclose.

Alan Goodstat, LCSW, Activity Planning Committee, has no relationships to disclose.

Cheryl C. Kay, Activity Planning Committee, has no relationships to disclose.
Commercial Support
This activity is supported by an educational grant from Grifols.